Fig. 2

Effects of uvaol on body weight gain (a), disease activity index (DAI) (b), colon length (c), myeloperoxidase (MPO) activity (d) and histological damage (magnification of 10 × for representative H&E staining images) (e) of DSS-treated mice. Uvaol was administered to mice from day 8 to day 14. Weight and DAI scores are measured every 2 days. DAI was determined by combining scores of (i) body weight loss, (ii) stool consistency, and (iii) stool bleeding. On day 14, the mice were sacrificed, the colon lengths and histological score of colons were measured. Data are expressed as mean ± SEM, n = 7.^###P < 0.001 and^##P < 0.01, compared with control group; ***P < 0.001, **P < 0.01 and *P < 0.05, compared with DSS group