Fig. 6

H&E staining of tissues with different treatments on day 7, 14 and 28, 200×. a CA on day 7, PMNL infiltration with active fibroblast proliferation in the granulation tissue; b TA1 on day 7, similar findings as CA with brownish foreign body debris (black arrow); c TA2 on day 7, similar findings as CA with brownish foreign body debris (black arrow); d TA3 on day 7, similar findings as CA with brownish foreign body debris (black arrow); e CA on day 14, mineralized foreign body debris with diffuse fibroblast infiltration; f TA1 on day 14, diffuse fibroblast infiltration with PMNL withdrawing. Note the brownish foreign body debris still located in the granulation tissue (black arrow); g TA2 on day 14, similar findings as TA1 on day 14 but with more PMNL infiltration; h TA3 on day 14, more PMNL infiltration but less fibroblast infiltration when compared to the TA1 group; i CA on day 28, the wound was refilled without notable PMNL infiltration; j TA1 on day 28, more collagen deposition than CA group. Only a few foreign body debris observed in the granulation tissue (black arrow); k TA2 on day 28, neovascularization present in the granulation tissue with sporadic foreign body debris accumulated (black arrow); l TA3 on day 28, similar findings as TA2 on day 28 with more PMNL infiltration