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Table 4 Effects of liguzinediol on HMI and LVMI in MI rats

From: The protective effects of liguzinediol on congestive heart failure induced by myocardial infarction and its relative mechanism

Group Dose (mg/kg) HMI (mg/g) LVMI (mg/g)
Sham 2.63 ± 0.21 1.85 ± 0.21
MI 3.53 ± 0.30** 2.36 ± 0.43**
Captopril 10 2.88 ± 0.31##* 1.99 ± 0.21#
Digoxin 0.032 2.9 ± 0.13##** 2.06 ± 0.09#**
Liguzinediol 5 2.95 ± 0.44## 2.09 ± 0.31
10 2.69 ± 0.23## 1.95 ± 0.18#
20 2.69 ± 0.20## 1.92 ± 0.16##
  1. Sham, sham-operated; MI, myocardial infarction; HMI, heart mass index, HMI = HM (heart mass)/BM (body mass); LVMI, left ventricular mass index, LVMI = LVM (left ventricular mass)/BM
  2. Data are shown as the mean ± SD (n = 10). *P < 0.05, **P < 0.01, compared to Sham group; #P < 0.05, ##P < 0.01, compared to MI group