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Table 4 Effects of liguzinediol on HMI and LVMI in MI rats

From: The protective effects of liguzinediol on congestive heart failure induced by myocardial infarction and its relative mechanism

Group

Dose (mg/kg)

HMI (mg/g)

LVMI (mg/g)

Sham

–

2.63 ± 0.21

1.85 ± 0.21

MI

–

3.53 ± 0.30**

2.36 ± 0.43**

Captopril

10

2.88 ± 0.31##*

1.99 ± 0.21#

Digoxin

0.032

2.9 ± 0.13##**

2.06 ± 0.09#**

Liguzinediol

5

2.95 ± 0.44##

2.09 ± 0.31

10

2.69 ± 0.23##

1.95 ± 0.18#

20

2.69 ± 0.20##

1.92 ± 0.16##

  1. Sham, sham-operated; MI, myocardial infarction; HMI, heart mass index, HMI = HM (heart mass)/BM (body mass); LVMI, left ventricular mass index, LVMI = LVM (left ventricular mass)/BM
  2. Data are shown as the mean ± SD (n = 10). *P < 0.05, **P < 0.01, compared to Sham group; #P < 0.05, ##P < 0.01, compared to MI group
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Chinese Medicine

ISSN: 1749-8546

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