Analyte | AUC0→t (ng h/mL) | AUC0→∞ (ng h/mL) | MRT0→t (h) | MRT0→∞ (h) | t1/2 (h) | Tmax (h) | Cmax (ng/mL) |
---|---|---|---|---|---|---|---|
1 | 108.74 ± 11.40 | 115.09 ± 15.76 | 2.60 ± 0.12 | 3.37 ± 0.26 | 1.79 ± 0.44 | 2.00 ± 0.00 | 47.99 ± 4.41 |
2 | 2967.61 ± 169.49 | 3110.48 ± 38.66 | 6.51 ± 0.66 | 8.09 ± 1.32 | 5.27 ± 2.94 | 2.17 ± 0.76 | 477.02 ± 33.31 |
3 | 463.00 ± 29.50 | 489.12 ± 37.60 | 3.67 ± 0.14 | 4.32 ± 0.47 | 2.66 ± 0.69 | 2.33 ± 0.58 | 101.53 ± 18.42 |
4 | 80.47 ± 9.64 | 92.61 ± 21.43 | 2.38 ± 0.24 | 3.25 ± 0.41 | 2.20 ± 1.24 | 1.00 ± 0.50 | 46.84 ± 6.78 |
5 | 344.22 ± 43.08 | 504.72 ± 108.63 | 3.51 ± 0.24 | 7.55 ± 1.93 | 3.89 ± 0.85 | 1.00 ± 0.43 | 103.90 ± 14.93 |
6 | 466.39 ± 51.94 | 1012.04 ± 558.43 | 9.19 ± 1.00 | 13.95 ± 9.49 | 10.49 ± 6.63 | 0.08 ± 0.00 | 79.85 ± 9.43 |
7 | 468.14 ± 48.36 | 550.30 ± 70.65 | 9.04 ± 0.68 | 14.25 ± 3.28 | 7.68 ± 3.01 | 0.17 ± 0.00 | 87.65 ± 26.65 |
8 | 1800.70 ± 154.66 | 2142.54 ± 167.73 | 2.88 ± 0.15 | 4.31 ± 0.67 | 2.70 ± 0.54 | 1.67 ± 0.29 | 432.72 ± 53.10 |
9 | 1090.97 ± 109.82 | 2548.08 ± 277.22 | 8.96 ± 0.40 | 10.52 ± 4.72 | 9.65 ± 4.91 | 1.83 ± 0.29 | 269.68 ± 24.01 |
10 | 369.68 ± 155.83 | 374.65 ± 153.08 | 2.54 ± 1.12 | 3.13 ± 1.66 | 1.64 ± 0.52 | 1.33 ± 0.58 | 192.33 ± 31.98 |
11 | 691.13 ± 93.26 | 1638.89 ± 155.01 | 11.02 ± 0.99 | 14.16 ± 8.89 | 9.16 ± 2.09 | 1.67 ± 0.29 | 133.90 ± 31.78 |
12 | 441.56 ± 59.51 | 480.47 ± 71.86 | 2.45 ± 0.19 | 3.10 ± 0.33 | 1.79 ± 0.20 | 1.00 ± 0.43 | 186.20 ± 19.02 |
13 | 3803.21 ± 170.75 | 5627.52 ± 2430.69 | 8.04 ± 0.88 | 39.04 ± 46.48 | 38.76 ± 53.16 | 8.00 ± 0.00 | 619.12 ± 84.57 |
14 | 143.85 ± 16.54 | 205.76 ± 58.66 | 6.67 ± 1.42 | 17.02 ± 8.17 | 12.11 ± 9.32 | 2.00 ± 0.00 | 67.74 ± 27.55 |
15 | 74.29 ± 17.48 | 81.11 ± 19.35 | 2.21 ± 0.48 | 3.05 ± 1.01 | 1.20 ± 0.74 | 1.42 ± 0.63 | 47.74 ± 5.92 |
16 | 177.10 ± 17.10 | 250.82 ± 97.56 | 8.68 ± 1.17 | 20.144 ± 5.01 | 12.64 ± 12.72 | 2.00 ± 0.00 | 31.45 ± 6.94 |
17 | 160.80 ± 12.69 | 178.64 ± 14.30 | 7.30 ± 0.38 | 9.82 ± 0.45 | 5.98 ± 0.40 | 3.33 ± 2.31 | 19.20 ± 2.48 |
18 | 74.65 ± 8.31 | 193.63 ± 27.92 | 9.85 ± 0.85 | 48.18 ± 39.82 | 33.59 ± 27.13 | 1.83 ± 0.29 | 10.19 ± 0.58 |
19 | 248.66 ± 65.48 | 251.96 ± 62.45 | 2.44 ± 0.12 | 2.55 ± 0.21 | 1.10 ± 0.47 | 2.00 ± 0.00 | 169.08 ± 73.48 |