Fig. 7

Effect of GATE on oxidative stress and TNF-α expression in ADR-induced NS mice. At the end of experiment, blood and left kidneys of mice from different groups were collected. Then plasma SOD activity (a) and MDA level (b), renal tissue SOD activity (c), MDA level (d) and ROS level (e) were measured using the corresponding assay kits. f Representative Western blots of TNF-α expression in kidney tissues from different groups on day 25. g The plasma TNF-α level of mice in each group was determined by ELISA on day 25. The data were expressed as means ± SEM. *p < 0.05, **p < 0.01 compared with control group; ^#p < 0.05, ^##p < 0.01 compared with model group