Fig. 4

Neuroprotective effects of RAGE on tMCAO-induced hippocampal CA1 cell death. A, representative photomicrographs of cresyl violet-stained, H&E-stained, and IHC-stained (TNF-α and IL-6, respectively) hippocampal CA1 region. B and C, quantitative analysis of the TNF-α and IL-6 expression in tMCAO-induced hippocampal CA1 region using the ELISA method. All data are expressed as mean ± standard error (n = 3). ^### p < 0.001 vs. sham-operated group; * p < 0.05, ** p < 0.01 vs. tMCAO group