Table 4 Results of integrating pathway analysis with MetaboAnalyst 4.0
No | Pathway Name | Match status | p | − log(p) | Impact |
|---|---|---|---|---|---|
1 | Glycerophospholipid metabolism | 3/36 | 0.00064401 | 7.3478 | 0.21631 |
2 | Biosynthesis of unsaturated fatty acids | 2/36 | 0.014161 | 4.2573 | 0 |
3 | Fatty acid degradation | 2/39 | 0.016523 | 4.103 | 0.12404 |
4 | Linoleic acid metabolism | 1/5 | 0.026263 | 3.6396 | 0 |
5 | Alpha-Linolenic acid metabolism | 1/13 | 0.067028 | 2.7026 | 0 |
6 | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis | 1/14 | 0.072017 | 2.6308 | 0.00399 |
7 | Pantothenate and CoA biosynthesis | 1/19 | 0.096614 | 2.337 | 0.175 |
8 | Citrate cycle (TCA cycle) | 1/20 | 0.10146 | 2.288 | 0.08764 |
9 | Pyruvate metabolism | 1/22 | 0.1111 | 2.1973 | 0 |
10 | Arachidonic acid metabolism | 1/36 | 0.17603 | 1.7371 | 0 |
11 | Fatty acid elongation | 1/39 | 0.18939 | 1.6639 | 0 |
12 | Fatty acid biosynthesis | 1/47 | 0.2241 | 1.4957 | 0.01472 |