Fig. 5
From: Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration
ROS involvement in OPE-induced liver cancer cell apoptosis. a HepG2 and SMMC-7721 cells were treated with OPE at indicated doses (0, 3.125, and 6.25 μg/mL) for 48 h, followed by analysis of ROS by flow cytometry. b Cells were treated with OPE plus NAC (5 mM) for 48 h, and cell viability was determined by using CCK-8 assay. Data are presented as mean ± SD of at least three independent experiments. (*p < 0.05; ***p < 0.001, compared to untreated control)