Table 3 Main GO pathways significantly relating to major hubs
Term | Pathway | Count | Pop hits | P Value |
|---|---|---|---|---|
GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | 32 | 981 | 9.79E−16 |
GO:0043066 | Negative regulation of apoptotic process | 25 | 455 | 4.13E−17 |
GO:0045893 | Positive regulation of transcription, DNA-templated | 24 | 515 | 8.12E−15 |
GO:0007165 | Signal transduction | 21 | 1161 | 6.17E−06 |
GO:0010628 | Positive regulation of gene expression | 18 | 262 | 9.90E−14 |
GO:0042493 | Response to drug | 17 | 304 | 1.37E−11 |
GO:0006915 | Apoptotic process | 17 | 567 | 1.08E−07 |
GO:0006954 | Inflammatory response | 16 | 379 | 3.26E−09 |
GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | 16 | 720 | 1.19E−05 |
GO:0008285 | Negative regulation of cell proliferation | 15 | 396 | 4.72E−08 |
GO:0032355 | Response to estradiol | 14 | 91 | 3.49E−15 |
GO:0008284 | Positive regulation of cell proliferation | 14 | 466 | 2.15E−06 |
GO:0071456 | Cellular response to hypoxia | 13 | 96 | 2.22E−13 |
GO:0001525 | Angiogenesis | 13 | 223 | 4.64E−09 |
GO:0006468 | Protein phosphorylation | 13 | 456 | 9.88E−06 |
GO:0045892 | Negative regulation of transcription, DNA-templated | 13 | 499 | 2.42E−05 |
GO:0001666 | Response to hypoxia | 12 | 172 | 3.51E−09 |
GO:0006974 | Cellular response to DNA damage stimulus | 12 | 208 | 2.54E−08 |
GO:0000165 | MAPK cascade | 12 | 262 | 2.66E−07 |
GO:0008283 | Cell proliferation | 12 | 366 | 6.90E−06 |