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Fig. 3 | Chinese Medicine

Fig. 3

From: Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells

Fig. 3

SKO induced degradation of cIAP1, cIAP2 and RIP1 in MDA-MB-231 cells. a The expression of cIAP1, cIAP2 and RIP1 in cells treated with SKO at the indicated concentrations for 12 h. b Semi-quantitative the expression of cIAP1, cIAP2 and RIP1 in cells treated with SKO at the indicated concentrations for 12 h. c The expression of XIAP, FADD, DR5 and DR4 in cells treated with SKO at the indicated concentrations for 12 h. d Semi-quantitative the expression of XIAP, FADD, DR5 and DR4 in cells treated with SKO at the indicated concentrations for 12 h. Data was represented as means ± SEM. **p < 0.01 vs. untreated control group

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Chinese Medicine

ISSN: 1749-8546

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