Table 3 Key nodes of ”AE-component-target-COVID” network and their topological characteristics
From: The important herbal pair for the treatment of COVID-19 and its possible mechanisms
Components | Betweenness centrality | Degree | Targets | Betweenness centrality | Degree |
|---|---|---|---|---|---|
Quercetin | 0.258 | 39 | PTGS2 | 0.209 | 29 |
Luteolin | 0.068 | 19 | PTGS1 | 0.147 | 25 |
Kaempferol | 0.032 | 14 | PPARG | 0.036 | 13 |
Naringenin | 0.025 | 11 | NOS2 | 0.019 | 9 |
β-sitosterol | 0.013 | 8 | RELA | 0.007 | 6 |
(+)-catechin | 0.007 | 8 | CASP3 | 0.006 | 6 |
Stigmasterol | 0.003 | 6 | SOD1 | 0.009 | 5 |
Licochalcone B | 0.008 | 6 | MAPK14 | 0.010 | 5 |
Taxifolin | 0.004 | 5 | ICAM1 | 0.005 | 5 |
Glycyrol | 0.005 | 5 | HMOX1 | 0.006 | 5 |
Glabridin | 0.005 | 5 | CAT | 0.003 | 5 |