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Table 3 Key nodes of ”AE-component-target-COVID” network and their topological characteristics

From: The important herbal pair for the treatment of COVID-19 and its possible mechanisms

Components Betweenness centrality Degree Targets Betweenness centrality Degree
Quercetin 0.258 39 PTGS2 0.209 29
Luteolin 0.068 19 PTGS1 0.147 25
Kaempferol 0.032 14 PPARG 0.036 13
Naringenin 0.025 11 NOS2 0.019 9
β-sitosterol 0.013 8 RELA 0.007 6
(+)-catechin 0.007 8 CASP3 0.006 6
Stigmasterol 0.003 6 SOD1 0.009 5
Licochalcone B 0.008 6 MAPK14 0.010 5
Taxifolin 0.004 5 ICAM1 0.005 5
Glycyrol 0.005 5 HMOX1 0.006 5
Glabridin 0.005 5 CAT 0.003 5