Fig. 3
From: Honeysuckle-derived microRNA2911 inhibits tumor growth by targeting TGF-β1
Identification of TGF-β1 as a target of miR2911 in vitro. a Schematic description of the base pairing between miR2911 and TGF-β1 mRNA (mouse and human), and their binding energies. b Luciferase activity of HEK293T cells co-transfected with firefly luciferase reporters with miR2911 or NC microRNA treatment. WT wild type firefly luciferase reporters with normal TGF-β1, Mutant firefly luciferase reporters with mutant TGF-β1 3′-UTR. c The expression levels of TGF-β1 of CT26 cells in the mock group, the ncRNA-treated group and the miR2911-treated group. Data represent mean ± s.e.m., n = 3 per group. *P < 0.05 was significant different between ncRNA-treated group and miR2911-treated group