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Fig. 2 | Chinese Medicine

Fig. 2

From: Cerebralcare GranuleĀ® enhances memantine hydrochloride efficacy in APP/PS1 mice by ameliorating amyloid pathology and cognitive functions

Fig. 2

The scheme of experiment and MWM test. a The scheme of experiment to determine the effect of CG on APP/PS1 memory loss. bā€“f MWM test was conducted on APP/PS1 mice. b The representative traces on the last day during acquisition phase. c Escape latency trend for six consecutive days. d Escape latency on the sixth day. e Times of passing through platform. f Time in the target quadrant. ^ Pā€‰<ā€‰0.05, ^^ Pā€‰<ā€‰0.01, ^^^ Pā€‰<ā€‰0.01 vs. WT group; * Pā€‰<ā€‰0.05, ** Pā€‰<ā€‰0.01, *** Pā€‰<ā€‰0.01 vs. Tg group; # Pā€‰<ā€‰0.05, ## Pā€‰<ā€‰0.001, ### Pā€‰<ā€‰0.001, vs. Mm group, & Pā€‰<ā€‰0.05, && Pā€‰<ā€‰0.001, &&& Pā€‰<ā€‰0.001, vs. CG group (nā€‰=ā€‰10)

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