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Fig. 4 | Chinese Medicine

Fig. 4

From: Cerebralcare GranuleĀ® enhances memantine hydrochloride efficacy in APP/PS1 mice by ameliorating amyloid pathology and cognitive functions

Fig. 4

CG enhanced the effects of Mm on reducing AĪ² plaque deposition In the hippocampus. a Immunofluorescence for AĪ² in the hippocampus of the APP/PS1 mice. Scale barā€‰=ā€‰100Ā Ī¼m. b Mean fluorescence intensity of AĪ² plaques. c The protein levels of SYN, PSD95, GAP43, APPĪ², APPĪ±, APP, and BACE1 were measured by Western blotting in the hippocampus of the different groups (nā€‰=ā€‰10). dā€“j Quantitative analysis of SYN, PSD95, GAP43, APPĪ², APPĪ±, APP, and BACE1 expression, respectively. ^ Pā€‰<ā€‰0.05, ^^ Pā€‰<ā€‰0.01, ^^^ Pā€‰<ā€‰0.01 vs. WT group; * Pā€‰<ā€‰0.05, ** Pā€‰<ā€‰0.01, *** Pā€‰<ā€‰0.01 vs. Tg group; # Pā€‰<ā€‰0.05, ## Pā€‰<ā€‰0.001, ### Pā€‰<ā€‰0.001, vs. Mm group, & Pā€‰<ā€‰0.05, && Pā€‰<ā€‰0.001, &&& Pā€‰<ā€‰0.001, vs. CG group (nā€‰=ā€‰10)

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