Fig. 4From: Cerebralcare GranuleĀ® enhances memantine hydrochloride efficacy in APP/PS1 mice by ameliorating amyloid pathology and cognitive functionsCG enhanced the effects of Mm on reducing AĪ² plaque deposition In the hippocampus. a Immunofluorescence for AĪ² in the hippocampus of the APP/PS1 mice. Scale barā=ā100Ā Ī¼m. b Mean fluorescence intensity of AĪ² plaques. c The protein levels of SYN, PSD95, GAP43, APPĪ², APPĪ±, APP, and BACE1 were measured by Western blotting in the hippocampus of the different groups (nā=ā10). dāj Quantitative analysis of SYN, PSD95, GAP43, APPĪ², APPĪ±, APP, and BACE1 expression, respectively. ^ Pā<ā0.05, ^^ Pā<ā0.01, ^^^ Pā<ā0.01 vs. WT group; * Pā<ā0.05, ** Pā<ā0.01, *** Pā<ā0.01 vs. Tg group; # Pā<ā0.05, ## Pā<ā0.001, ### Pā<ā0.001, vs. Mm group, & Pā<ā0.05, && Pā<ā0.001, &&& Pā<ā0.001, vs. CG group (nā=ā10)Back to article page