Fig. 5

The effect of TI on Akt/Nrf2 pathway. a, c H9c2 cells were pretreated with TI (0.25, 0.5, and 1 μM) for 2 h, and exposed to t-BHP (150 μM) for 4 h, therewith, the protein expression were detected by western blotting. Statistical analysis of protein expressions of b p-Akt/Akt, d Nrf2, e HO-1, f NQO-1. n = 3. ^*p < 0.05, ^**p < 0.01, ^***p < 0.00 vs. t-BHP group