Fig. 9From: Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathwayThe schematic of cardiovascular protective effects of TI in vitro. The mechanism of TI’s anti-oxidative effects and its effect on alleviating necroptosis in vitro was through Akt/Nrf2 and RIP1/RIP3/MLKL signaling pathwaysBack to article page