Table 1 Chinese herbal formulas exert an effect ongut mircrobiota
Chinese herbal formulas | Model | Regulatory effects on the microbiota | Key mechanisms | Ref |
|---|---|---|---|---|
Gegen Qinlian decoction | Rats | Firmicutes/Bacteroidetes ratio and Oscillibacter genus↑ | Improving the total amount and distribution of gut bacteria in rats | [52] |
Jiangzhiligan Decoction | Rats | Escherichia coli and Lactobacillus↓ | Adjusting the gut flora population of NAFLD rats and improving high-fat diet-induced NAFLD | [55] |
Huatan Huoxue Recipe | Rats | Parabacteroides and Butyrivibrio Bryant and Small↑ | Can partially restore the normal composition of the intestinal bacterial community | [64] |
Qiwei Tiexie capsule | Rats | Modulation of gut microbiota | Protecting the liver injury in differentiated 3T3-L1 adipocytes and NAFLD by regulating the LXRα, PPARγ, and NF-κB-iNOS-NO signal pathways | [84] |
Jianpi Huoxue Decoction | Rats | Regulating intestinal flora imbalance, and endotoxin production↓ | Reducing the liver cell damage | [121] |
Shenling Baizhu powder | Rats | Improving the abundance of intestinal microbiota, which including Actinobacteria, Bacteroidetes, Cyanobacteria, Firmicutes, Proteobacteria, TM7, and Verrucomicrobia, | Improving in intestinal permeability | [54] |
Yinchenhao decoction | Rats | Regulating the diversity of the Bacteroidetes, Actinobacteria and Proteobacteria | Involving in glycerophospholipid metabolism, purine metabolism, and glutathione metabolism | [92] |
Xiaozhi Decoction |  | Prevotella, Bifidobacterium, Escherichia coli, Fusobacterium and Lactobacillus↑ | Relating to the regulation and growth of beneficial gut microbiota | [122,123] |