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Table 1 Chinese herbal formulas exert an effect ongut mircrobiota

From: Herbal therapy for ameliorating nonalcoholic fatty liver disease via rebuilding the intestinal microecology

Chinese herbal formulas Model Regulatory effects on the microbiota Key mechanisms Ref
Gegen Qinlian decoction Rats Firmicutes/Bacteroidetes ratio and Oscillibacter genus↑ Improving the total amount and distribution of gut bacteria in rats [52]
Jiangzhiligan Decoction Rats Escherichia coli and Lactobacillus Adjusting the gut flora population of NAFLD rats and improving high-fat diet-induced NAFLD [55]
Huatan Huoxue Recipe Rats Parabacteroides and Butyrivibrio Bryant and Small↑ Can partially restore the normal composition of the intestinal bacterial community [64]
Qiwei Tiexie capsule Rats Modulation of gut microbiota Protecting the liver injury in differentiated 3T3-L1 adipocytes and NAFLD by regulating the
LXRα, PPARγ, and NF-κB-iNOS-NO signal pathways
Jianpi Huoxue Decoction Rats Regulating intestinal flora imbalance, and endotoxin production↓ Reducing the liver cell damage [121]
Shenling Baizhu powder Rats Improving the abundance of intestinal microbiota, which including Actinobacteria, Bacteroidetes, Cyanobacteria, Firmicutes, Proteobacteria, TM7, and Verrucomicrobia, Improving in intestinal permeability [54]
Yinchenhao decoction Rats Regulating the diversity of the Bacteroidetes, Actinobacteria and Proteobacteria Involving in glycerophospholipid metabolism, purine metabolism, and glutathione metabolism [92]
Xiaozhi Decoction   Prevotella, Bifidobacterium, Escherichia coli, Fusobacterium and Lactobacillus Relating to the regulation and growth of beneficial gut microbiota [122,123]