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Fig. 5 | Chinese Medicine

Fig. 5

From: Shenzhi Jiannao formula ameliorates vascular dementia in vivo and in vitro by inhibition glutamate neurotoxicity via promoting clathrin-mediated endocytosis

Fig. 5

Effects of SZJN formula on the expression of clathrin, RAB5B, and NMDAR1 by using immunofluorescence. Representative photomicrographs of A clathrin (green, AF488), B RAB5B (red, AF594), and C NMDAR1 (red, AF594) immunofluorescence are shown. Nuclei were stained with Hoechst 33342 (blue). The graph show the mean fluorescence intensity of D clathrin, E RAB5B, and F NMDAR1 in PC12 cells. SZJN-L: 0.05 mg/mL, SZJN-M: 0.1 mg/mL, SZJN-H: 0.2 mg/mL. Values were expressed as means ± SD (n = 3). *P < 0.05, **P < 0.01 as compared with the control group. #P < 0.05, ##P < 0.01 as compared with the glutamate group

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Chinese Medicine

ISSN: 1749-8546

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