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Fig. 2 | Chinese Medicine

Fig. 2

From: Two methoxy derivatives of resveratrol, 3,3′,4,5′-tetramethoxy-trans-stilbene and 3,4′,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF-κB pathways in RAW 264.7 cells

Fig. 2

Effects of 3,3′4,5′-TMS and 3,4′,5-TMS on cell viability, NO release and morphology in RAW 264.7 cells. a, b Cell viability of RAW 264.7 cells treated with different concentrations (5, 10, 30, 50 µM) of 3,3′4,5′-TMS and 3,4′,5-TMS for 24 h. c, d NO release in RAW 264.7 cells pretreated with 3,3′,4,5′-TMS or 3,4′,5-TMS (10 and 50 µM) for 4 h and then co-treated with lipopolysaccharides (LPS, 1 µg/mL) for another 12 h. Data are expressed as the mean ± SEM, n = 3. #P < 0.05 vs control. *P < 0.05 vs LPS. e Morphology of RAW 264.7 cells from different groups was visualized by optical microscopy (×10)

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