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Fig. 9 | Chinese Medicine

Fig. 9

From: Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation

Fig. 9

The potential role of WMW in TNBS-induced colitis in mice. WMW treatment can regulate colonic OGT and OGA activities, that is, enhance OGT activity and suppress OGA activity. These changes promote RIPK3 O-GlcNAcylation, thereby reducing RIPK3 activation and necrosome formation, and eventually inhibiting necroptosis and alleviating colitis

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Chinese Medicine

ISSN: 1749-8546

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