Fig. 4

Effects of YZR-0.4 g and YZR-0.8 g treatments on cytosolic p-JNK, JNK, p-p38 MAPK, p38 MAPK, iNOS, COX-2, and TNF-α expression in the penumbral cortex. A Representative Western blot images showed cytosolic p-JNK, JNK, p-p38 MAPK, p38 MAPK, iNOS, COX-2, and TNF-α expression in the penumbral cortex in the Sham, Control, YZR-0.2 g, YZR-0.4 g, and YZR-0.8 g groups (n = 5) at 1 day after reperfusion. The ratios of B p-JNK/JNK, C p-p38 MAPK/p38 MAPK, D iNOS/actin, E COX-2/actin, and F TNF-α/actin were measured in the penumbral cortex among the experimental groups. *P < 0.05 vs. the Sham group; ^#P < 0.05 vs. the Control group