Fig. 10

Enriched terms network, molecular docking, and pathway verification. A Network of enriched terms: colored by cluster ID, where nodes that share the same cluster ID are typically close to each other. Each term was represented by a circle node, where its size was proportional to the number of input genes fall into that term, and its color represent the cluster identity. Terms with a similarity score > 0.3 are linked by an edge. One term from each cluster is selected to have its term description shown as label. MCODE algorithm was then applied to this network to identify neighborhoods where proteins are densely connected. Each MCODE network is assigned a unique color. MCODE 1 was red and MCODE2 was blue. B Active ingredients docking with overlapped genes-IL6: blue structure was protein surface and below it: left panel is the overall view; the right panel is the focused view. C Active ingredients docking with overlapped genes-DGKA: blue structure was protein surface and below it: left panel is the overall view; the right panel is the focused view. D Bacterial adhesion assay with Pingwei Pill concentration (0 μg/mL or DMSO, 256 μg/mL, 512 μg/mL, 1024 μg/mL) combined colistin E (2 μg/mL). E Bacterial invasion assay with Pingwei Pill concentration (0 μg/mL or DMSO, 256 μg/mL, 512 μg/mL, 1024 μg/mL) combined colistin E (2 μg/mL)