Table 2 Aloin and osteosarcoma intersection gene list (54 genes)
From: Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma
Gene name | Uniprot ID | Protein name |
|---|---|---|
NOS2 | P35228 | Nitric oxide synthase, inducible |
FGFR1 | P11362 | Fibroblast growth factor receptor 1 |
GSTP1 | P09211 | Glutathione S-transferase P |
AURKA | O14965 | Aurora kinase A |
DHFR | P00374 | Dihydrofolate reductase |
GC | P02774 | Vitamin D-binding protein |
CTSB | P07858 | Cathepsin B |
KIT | P10721 | Mast/stem cell growth factor receptor Kit |
JAK2 | O60674 | Tyrosine-protein kinase JAK2 |
XIAP | P98170 | E3 ubiquitin-protein ligase XIAP |
CTSK | P43235 | Cathepsin K |
ESR1 | P03372 | Estrogen receptor |
TYMS | Q53Y97 | Thymidylate synthase |
CCNA2 | P20248 | Cyclin-A2 |
HMGCR | P04035 | 3-hydroxy-3-methylglutaryl-coenzymeA reductase |
MMP3 | P08254 | Stromelysin-1 |
MMP8 | P22894 | Neutrophil collagenase |
PGF | P49763 | Placenta growth factor |
EGFR | P00533 | Epidermal growth factor receptor |
MAPK8 | P45983 | Mitogen-activated protein kinase 8 |
SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src |
CDK2 | P24941 | Cyclin-dependent kinase 2 |
CCL5 | P13501 | C–C motif chemokine 5 |
ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 |
REN | P00797 | Renin |
ALB | P02768 | Albumin |
ESR2 | Q92731 | Estrogen receptor beta |
APRT | P07741 | Adenine phosphoribosyltransferase |
ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 |
PLAU | P00749 | Urokinase-type plasminogen activator |
MMP13 | P45452 | Collagenase 3 |
EPHA2 | P29317 | Ephrin type-A receptor 2 |
RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 |
CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 |
PPARG | P37231 | Peroxisome proliferator-activated receptor gamma |
RHOA | P61586 | Transforming protein RhoA |
PIM1 | P11309 | Serine/threonine-protein kinase pim-1 |
MAPK14 | Q16539 | Mitogen-activated protein kinase 14 |
CDK6 | Q00534 | Cyclin-dependent kinase 6 |
TGFBR1 | P36897 | TGF-beta receptor type-1 |
CTSD | P07339 | Cathepsin D |
ANXA5 | P08758 | Annexin A5 |
HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha |
CASP3 | P42574 | Caspase-3 |
PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 |
KDR | P35968 | Vascular endothelial growth factor receptor 2 |
TTR | P02766 | Transthyretin |
SYK | P43405 | Tyrosine-protein kinase SYK |
IGF1R | P08069 | Insulin-like growth factor 1 receptor |
AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase |
NR1I2 | O75469 | Nuclear receptor subfamily 1 group I member 2 |
AR | P10275 | Androgen receptor |
MMP7 | P09237 | Matrilysin |
GSK3B | P49841 | Glycogen synthase kinase-3 beta |