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Table 2 Preliminary screening of single-factor Cox proportional hazard model

From: A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation

Gene

Coef

Exp (coef)

z

P value

Lower. 95

Upper. 95

MET

0.600

1.822

5.595

2.200E−08

1.476

2.247

ARNTL2

0.569

1.766

5.402

6.580E−08

1.437

2.171

TLE2

− 0.698

0.498

− 5.176

2.270E−07

0.382

0.648

FAM83A

0.202

1.224

5.041

4.630E−07

1.132

1.325

KIF23

0.564

1.758

4.960

7.040E−07

1.407

2.196

ANLN

0.458

1.580

4.919

8.680E−07

1.317

1.896

LAMA3

0.412

1.510

4.877

1.080E−06

1.279

1.781

NUSAP1

0.671

1.957

4.805

1.550E−06

1.488

2.573

TSPOAP1

− 0.400

0.670

− 4.784

1.720E−06

0.569

0.790

ECT2

0.590

1.805

4.775

1.800E−06

1.416

2.300

FAM111B

0.617

1.854

4.763

1.910E−06

1.438

2.390

ANO1

0.520

1.682

4.740

2.130E−06

1.357

2.086

CKAP2L

0.525

1.690

4.739

2.150E−06

1.360

2.100

CEP55

0.517

1.677

4.690

2.730E−06

1.351

2.081

ADGRG6

0.437

1.548

4.686

2.780E−06

1.289

1.858

CA12

0.278

1.321

4.683

2.830E−06

1.176

1.484

DLGAP5

0.507

1.660

4.665

3.090E−06

1.342

2.054

DEPDC1

0.423

1.527

4.614

3.940E−06

1.276

1.828

EREG

0.205

1.227

4.610

4.030E−06

1.125

1.339

MMP28

0.397

1.488

4.601

4.210E−06

1.256

1.762

TPX2

0.457

1.580

4.587

4.500E−06

1.299

1.920

CENPE

0.600

1.822

4.585

4.540E−06

1.410

2.355

INPP4B

0.543

1.722

4.566

4.970E−06

1.363

2.174

GPR87

0.188

1.207

4.566

4.980E−06

1.113

1.309

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Chinese Medicine

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