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Fig. 11 | Chinese Medicine

Fig. 11

From: Compound traditional Chinese medicine dermatitis ointment ameliorates inflammatory responses and dysregulation of itch-related molecules in atopic dermatitis

Fig. 11

Effects of CTCMDO on DNCB-induced expression levels of proinflammatory markers in mice. ERK, p38, JNK, and NF-κB p65 levels. The proinflammatory expression levels were determined using western blot analysis. The results are representative of three separate experiments. NOR normal control, DNCB DNCB-sensitized mice, DEX dexamethasone (0.1 g/cm2) + DNCB-sensitized mice. CTCMDO-L (75 mg/g, crude drug/ointment, 0.1 g/cm2) + DNCB-sensitized mice. CTCMDO-M (150 mg/g, crude drug/ointment, 0.1 g/cm2) + DNCB-sensitized mice and CTCMDO-H (300 mg/g, crude drug/ointment, 0.1 g/cm2) + DNCB-sensitized mice. **P < 0.01, *P < 0.05 compared with the DNCB group, ## P < 0.01 compared with the NOR group

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