Table 4 Comparison of clinical symptom disappearance rate between Ludangshen and placebo group
Variables | FAS analysis | PPS analysis | ||||
|---|---|---|---|---|---|---|
Ludangshen | Placebo | P value | Ludangshen | Placebo | P value | |
Fatigue (n) | 94 | 90 | 92 | 89 | ||
Week 1 | 5 (5.3) | 0 (0.0) | 0.027 | 5 (5.4) | 0 (0.0) | 0.026 |
Week 2 | 35 (5.3) | 8 (8.9) | < 0.001 | 34 (36.7) | 8 (9.0) | < 0.001 |
Anorexia (n) | 68 | 70 | 67 | 68 | ||
Week 1 | 10 (14.7) | 3 (4.3) | 0.036 | 10 (14.9) | 3 (4.4) | 0.038 |
Week 2 | 39 (57.4) | 15 (21.4) | < 0.001 | 39 (58.2) | 14 (20.6) | < 0.001 |
Distention (n) | 43 | 34 | 42 | 33 | ||
Week 1 | 10 (23.3) | 4 (11.8) | 0.194 | 10 (23.8) | 4 (12.1) | 0.197 |
Week 2 | 29 (67.4) | 12 (35.3) | 0.005 | 29 (69.1) | 11 (33.3) | 0.002 |
Loose stools (n) | 48 | 52 | 48 | 50 | ||
Week 1 | 11 (22.9) | 5 (9.6) | 0.07 | 11 (22.9) | 5 (10.0) | 0.058 |
Week 2 | 32 (66.7) | 20 (38.5) | 0.005 | 32 (66.7) | 18 (36.0) | 0.002 |
Shortness of breath (n) | 50 | 50 | 49 | 49 | ||
Week 1 | 0 (0.0) | 0 (0.0) | 1.000 | 0 (0.0) | 0 (0.0) | 1.000 |
Week 2 | 8 (16.0) | 3 (6.0) | 0.110 | 8 (16.3) | 3 (6.1) | 0.110 |