Fig. 6

Treatment of CUMS-exposed rats with SSD results in elevated expression of p-mTOR, p-p70s6k, and p-4E-BP1 in the hippocampal CA1 region. IHC labeling at the original magnification (× 200 and × 400) and the respective IOD values of p-mTOR (A, B), p-p70s6k (C, D), and p-4EBP1(E, F) expression in the hippocampal CA1 region of CUMS rats. (G–I) show representative western blot images and the relative ratios of p-mTOR, p-p70s6k, and p-4EBP1 expression in the hippocampal CA1 regions of the different groups of CUMS-exposed rats. All data are expressed as the mean ± SD. ^*P < 0.05 compared to the control group, ^#P < 0.05 compared to the CUMS group; n = 6