Fig.6

Crowberry suppresses cell proliferation and migration by regulating DEK. The expression of DEK in HIBEpic, HuCCT1, QBC939, REE, TFK1 and after treatment with crowberry for 48 h in HuCCT1 was dectected by western blotting. The statistical chart of western blotting assays is attaching (A and B). The effect of gene silencing and overprseeion was presented by western blotting (C). After the DEK gene was silenced and overpressed, the effects on cell proliferation, migration shown in (D–F). *P < 0.05, **P < 0.01 (vs CON in siDEK group, vs Vector in overexpression group, n = 3). Original magnifications, × 40 (F). Original magnifications, × 200 (G). CON, control. NC, negative control