Table 1 The effect of JTG on bone biomechanical parameters in OVX rat (n = 10, means ± SD)
Group | Simple size (mm) | Elastic modulus (MPa) | Maximum load (N) | Maximum stress (MPa) | Bending stiffness (N/mm2) | Maximum strain (mm/mm) | Material toughness (KJ) |
|---|---|---|---|---|---|---|---|
Sham | 3.15 ± 0.16 | 7723.82 ± 1218.10 | 143.49 ± 7.88 | 184.68 ± 23.71 | 35,207.68 ± 5452.17 | 0.058 ± 0.009 | 60.28 ± 6.24 |
OVX | 3.08 ± 0.14 | 5419.00 ± 776.01### | 126.88 ± 9.93## | 153.59 ± 15.30### | 27,506.02 ± 5241.84### | 0.057 ± 0.013 | 48.63 ± 7.61# |
E2V | 3.14 ± 0.08 | 7944.48 ± 714.80*** | 146.10 ± 16.08*** | 189.70 ± 10.85*** | 35,612.25 ± 3178.47*** | 0.057 ± 0.006 | 56.76 ± 7.28 |
JTG-180 mg/kg | 3.09 ± 0.14 | 6924.44 ± 764.04** | 145.56 ± 9.67*** | 175.31 ± 12.85** | 33,837.09 ± 3103.59** | 0.059 ± 0.008 | 59.84 ± 6.65* |
JTG-360 mg/kg | 3.12 ± 0.13 | 7260.66 ± 765.78*** | 148.15 ± 13.46*** | 178.96 ± 13.71** | 34,854.07 ± 3922.87** | 0.057 ± 0.011 | 60.98 ± 9.67** |
JTG-720 mg/kg | 3.15 ± 0.18 | 7409.68 ± 1442.85*** | 148.30 ± 12.98*** | 180.75 ± 22.37*** | 35,384.66 ± 7091.08*** | 0.059 ± 0.006 | 60.63 ± 12.49* |