Table 2 Change from baseline for secondary outcome measures at different time points
Outcome | Total | P valuea | Successful Quit (n = 14) | Unsuccessful Quit (n = 16) | P valueb |
|---|---|---|---|---|---|
FTND | Â | Â | Â | Â | Â |
 Week 2 | − 0.80 (− 3.51 to − 0.08) | 0.03 | − 2.57 (− 5.44 to 0.30) | − 1.12 (− 3.27 to 1.02) | 0.18 |
 Week 4 | − 2.06 (− 3.77 to − 0.35) | 0.006 | − 3.07 (− 6.01 to − 0.12)* | − 1.18 (− 3.17 to 0.79) | 0.06 |
 Week 6 | − 2.50 (− 4.16 to − 0.84) |  < 0.001 | − 3.35 (− 6.21 to − 0.50)* | − 1.75 (− 3.70 to 0.20) | 0.08 |
 Week 8 | − 2.73 (− 4.49 to − 0.97) |  < 0.001 | − 4.35 (− 6.98 to − 1.72)‡ | − 1.31 (− 3.48 to 0.85) | 0.006 |
 Week 16 | − 2.73 (− 4.51 to − 0.95) |  < 0.001 | − 4.42 (− 7.02 to − 1.83)‡ | − 1.25 (− 3.44 to 0.94) | 0.004 |
 Week 24 | − 2.76 (− 4.48 to − 1.05) |  < 0.001 | − 4.78 (− 7.04 to − 2.52)‡ | − 1.00 (− 3.05 to 1.05) |  < 0.001 |
AUTOS | Â | Â | Â | Â | Â |
 Week 2 | − 3.30 (− 9.83 to 3.23) | 1.00 | − 4.85 (− 14.43 to 4.72) | − 1.93 (− 11.18 to 7.31) | 0.90 |
 Week 4 | − 5.83 (− 12.22 to 0.55) | 0.11 | − 9.07 (− 18.80 to 0.65) | − 3.00 (− 11.74 to 5.74) | 0.10 |
 Week 6 | − 8.93 (− 14.82 to − 3.04) |  < 0.001 | − 12.14 (− 21.65 to − 2.62)†| − 6.12 (− 13.62 to 1.37) | 0.24 |
 Week 8 | − 10.73 (− 16.55 to − 4.91) |  < 0.001 | − 14.00 (− 23.48 to − 4.51)†| − 7.87 (− 15.54 to − 0.20)* | 0.46 |
 Week 16 | − 12.56 (− 18.10 to − 7.02) |  < 0.001 | − 17.50 (− 25.99 to − 9.00)‡ | − 8.25 (− 15.71 to − 0.78)* | 0.04 |
 Week 24 | − 13.03 (− 19.10 to − 6.96) |  < 0.001 | − 20.28 (− 27.89 to − 12.67)‡ | − 6.68 (− 15.09 to 1.72) |  < 0.001 |
HAM− A |  |  |  |  |  |
 Week 2 | − 0.86 (− 8.64 to 6.91) | 1.00 | − 2.00 (− 13.48 to 9.48) | 0.12 (− 10.29 to 10.54) | 0.40 |
 Week 4 | − 4.13 (− 11.69 to 3.42) | 1.00 | − 5.78 (− 17.48 to 5.91) | − 2.68 (− 12.35 to 6.97) | 0.60 |
 Week 6 | − 6.20 (− 13.54 to 1.14) | 0.20 | − 7.14 (− 19.51 to 5.23) | − 5.37 (− 13.85 to 3.10) | 0.55 |
 Week 8 | − 6.53 (− 13.82 to 0.75) | 0.12 | − 8.14 (− 20.17 to 3.89) | − 5.12 (− 14.00 to 3.75) | 0.80 |
 Week 16 | − 4.96 (− 12.13 to 2.20) | 0.66 | − 6.07 (− 17.98 to 5.84) | − 4.00 (− 12.62 to 4.62) | 0.36 |
 Week 24 | − 5.80 (− 13.08 to 1.48) | 0.29 | − 9.14 (− 20.44 to 2.15) | − 2.87 (− 12.80 to 7.05) | 0.97 |
SAS | Â | Â | Â | Â | Â |
 Week 2 | − 2.40 (− 8.61 to 3.81) | 1.00 | − 1.00 (− 11.45 to 9.45) | − 3.62 (− 11.52 to 4.27) | 0.23 |
 Week 4 | − 4.16 (− 9.97 to 1.64) | 0.55 | − 3.28 (− 13.06 to 6.48) | − 4.93 (− 12.41 to 2.54) | 0.26 |
 Week 6 | − 3.60 (− 8.82 to 1.62) | 0.66 | − 3.21 (− 12.43 to 6.01) | − 3.93 (− 10.54 to 2.67) | 0.47 |
 Week 8 | − 5.03 (− 10.95 to 0.89) | 0.19 | − 5.57 (− 16.06 to 4.92) | − 4.56 (− 11.92 to 2.79) | 0.86 |
 Week 16 | − 3.66 (− 8.99 to 1.65) | 0.67 | − 3.00 (− 12.28 to 6.28) | − 4.25 (− 11.06 to 2.56) | 0.27 |
 Week 24 | − 2.33 (− 7.58 to 2.91) | 1.00 | − 1.71 (− 10.77 to 7.34) | − 2.87 (− 9.71 to 3.96) | 0.37 |
PSQI | Â | Â | Â | Â | Â |
 Week 2 | − 0.80 (− 3.79 to 2.19) | 1.00 | − 1.00 (− 5.66 to 3.66) | − 0.62 (− 4.70 to 3.45) | 0.64 |
 Week 4 | − 1.26 (− 4.43 to 1.90) | 1.00 | − 1.57 (− 6.56 to 3.41) | − 1.00 (− 5.38 to 3.38) | 0.52 |
 Week 6 | − 1.53 (− 4.69 to 1.62) | 1.00 | − 1.85 (− 6.76 to 3.05) | − 1.25 (− 5.62 to 3.12) | 0.44 |
 Week 8 | − 1.60 (− 4.68 to 1.48) | 1.00 | − 1.85 (− 6.61 to 2.89) | − 1.37 (− 5.67 to 2.92) | 0.41 |
 Week 16 | − 1.53 (− 4.75 to 1.68) | 1.00 | − 2.00 (− 6.91 to 2.91) | − 1.12 (− 5.70 to 3.45) | 0.45 |
 Week 24 | − 1.66 (− 5.06 to 1.73) | 1.00 | − 2.85 (− 7.64 to 1.93) | − 0.62 (− 5.61 to 4.36) | 0.14 |