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Table 7 Logistic regressions between clinical variables and Traditional Chinese Medicine diagnostic patterns using the overall sample dataset (n = 400)

From: Quantification of prevalence, clinical characteristics, co-existence, and geographic variations of traditional Chinese medicine diagnostic patterns via latent tree analysis-based differentiation rules among functional dyspepsia patients

Clinical variable

TCM diagnostic pattern

SDDEd,e

LQISd,e

SSQDd,e

CHCd,e

SHd,e

SSDCd,e

SDQSd,e

SSDHd,e

Locate in Hong Konga

2.34 (1.15–4.74)

0.48 (0.25–0.94)

0.48 (0.18–1.29)

2.23 (1.18–4.21)

0.74 (0.41–1.35)

0.44 (0.18–1.08)

2.59 (1.05–6.40)

1.06 (0.45–2.51)

FD subtypeb

 Postprandial distress syndrome

0.73 (0.34–1.60)

0.63 (0.29–1.38)

3.20 (1.07–9.59)

0.97 (0.51–1.86)

1.86 (0.45–1.66)

2.24 (0.83–6.01)

1.32 (0.53–3.33)

1.06 (0.40–2.82)

 Epigastric pain syndrome

1.58 (0.62–4.07)

1.35

(0.52–3.52)

0.21

(0.05–0.92)

1.44

(0.62–3.33)

0.66 (0.27–1.61)

0.65 (0.19–2.17)

0.57 (0.17–1.94)

0.42 (0.11–1.63)

Without IBS diagnosisc

0.68 (0.30–1.55)

0.64 (0.29–1.39)

0.91 (0.29–2.81)

0.84 (0.41–1.74)

1.35 (0.67–2.70)

1.25 (0.48–3.24)

0.73 (0.29–1.85)

1.14 (0.47–2.74)

Higher PHQ9 score

1.01 (0.90–1.12)

1.08 (0.98–1.20)

1.08 (0.94–1.25)

1.01 (0.93–1.11)

1.00 (0.92–1.09)

1.06 (0.94–1.20)

0.97 (0.87–1.09)

1.00 (0.89–1.12)

Higher GAD7 score

1.09 (0.98–1.20)

1.20 (1.08–1.33)

1.02 (0.88–1.19)

0.92 (0.84–1.00)

1.02 (0.93–1.11)

0.95 (0.85–1.06)

1.03 (0.92–1.16)

0.91 (0.82–1.92)

Higher NDI symptom severity

1.00 (0.99–1.02)

1.00 (0.99–1.02)

1.00 (0.98–1.02)

1.00 (0.99–1.02)

1.02 (1.01–1.03)

0.99 (0.97–1.01)

1.03 (1.01–1.05)

1.01 (0.99–1.02)

Higher NDI QoL score(s)

 Eating/drinking

1.00 (0.98–1.02)

0.99 (0.98–1.01)

0.97 (0.94–0.99)

1.00 (0.98–1.01)

1.00 (0.99–1.02)

1.04 (1.01–1.07)

0.99 (0.97–1.01)

1.03 (1.01–1.05)

 Sleep disturbance

0.99 (0.97–1.00)

1.00 (0.99–1.02)

0.98 (0.96–1.00)

1.00 (0.99–1.01)

1.00 (0.98–1.01)

1.02 (0.99–1.04)

1.01 (0.99–1.03)

1.01 (0.99–1.03)

 Knowledge/control

1.04 (1.01–1.06)

0.99 (0.97–1.02)

1.03 (0.99–1.07)

0.99 (0.97–1.01)

0.99 (0.98–1.02)

1.01 (0.98–1.05)

0.97 (0.94–1.00)

0.98 (0.95–1.01)

 Interference

1.00 (0.97–1.03)

1.02 (0.99–1.05)

1.00 (0.95–1.04)

0.98 (0.95–1.00)

1.01 (0.99–1.04)

0.96 (0.91–1.00)

1.03 (0.99–1.06)

0.98 (0.95–1.02)

  1. Logistic regression model for each pair of Traditional Chinese Medicine (TCM) diagnostic patterns was adjusted for the remaining TCM diagnostic patterns. Statistically significant results are bolded and underlined
  2. CHC Cold-heat complex, FD functional dyspepsia, GAD7 7-item generalised anxiety disorder scale, IBS Irritable bowel syndrome, LQIS liver qi invading the stomach, NDI Nepean Dyspepsia Index, PHQ9 9-item patient’s health questionnaire, QoL Quality of life, SDQS Spleen deficiency and qi stagnation, SDDE Spleen deficiency with dampness encumbrance, SH Stomach heat, SSDC Spleen-stomach deficiency cold, SSDH Spleen-stomach dampness-heat, SSQD Spleen-stomach qi deficiency, TCM Traditional Chinese Medicine
  3. aReference group: Hunan sample
  4. bReference group: Overlapping between postprandial distress syndrome and epigastric pain syndrome
  5. cReference group: With concomitant IBS diagnosis
  6. dResults shown in adjusted odds ratios with 95% confidence intervals
  7. eP values of the Pearson and Deviance tests > 0.10, indicating good model fit