Fig. 3

Effect of tea on histopathology of rat kidney induced by PO- and hypoxanthine. The right kidney of the rat was fixed, embedded in paraffin, sectioned, and stained. a H&E. Scale bars, 100 μm. The blue, black, and yellow arrows indicate conspicuous dilation of renal tubules, fibroproliferative lesions and inflammatory infiltration, respectively. b Masson’s trichrome. Scale bars, 50 μm. c Immunohistochemistryfor F4/80. Scale bars, 50 μm. d Bar diagrams represent the area of interstitial fibrosis (%). e Quantification of the proportion of F4/80 -positive cells in the kidney