Fig. 6From: Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancerA and B Representative photographs, tumor volume measurement and tumor weight in H1688 or A549 xenograft mouse model at 21 d after NC treatment (n = 5). C The protein expression of PI3K, p-PI3K, Akt, p-Akt, GSDME, cas 3, cl-cas 3, Bcl-2, Bax and β-Actin in treated tumor tissues. Protein levels were expressed as mean ± SD (n = 5). *P < 0.01, **P < 0.05, ***P < 0.001 vs controlBack to article page