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Table 2 Linear regression equation, range, and correlation coefficient for the Tanreqing analytes in plasma samples

From: Pharmacokinetic study of the main components of Tanreqing capsules and Tanreqing injections in beagles by liquid chromatography–tandem mass spectrometry

Analyte

Regression equation

LLOQ (ng/mL)

Calibration range

(ng/mL)

r2

Baicalin

y = 0.002x + 1.021

2.00

2.00–1000.00

0.99

Ursodeoxycholic acid

y = 0.026x – 0.142

10.00

10.00–5000.00

0.99

Chenodeoxycholic acid

y = 0.038x − 0.020

1.00

1.00–500.00

0.99

Chlorogenic acid

y = 0.002x + 0.003

1.00

1.00–500.00

0.99

  1. x represents the measured concentration
  2. y represents the peak area ratio of compound to internal standard