Psoralea corylifolia L.: a comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control and pharmacokinetics

Chen, Lele; Chen, Shuguang; Sun, Peng; Liu, Xinyue; Zhan, Zhaoshuang; Wang, Jiafeng

doi:10.1186/s13020-022-00704-6

Table 2 Compounds isolated from PCL

From: Psoralea corylifolia L.: a comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control and pharmacokinetics

Class	NO	Chemical component	Chemical formula	References
Coumarins	1	psoralen	C₁₁H₆O₃	[9]
	2	isopsoralen	C₁₁H₆O₃	[10]
	3	5-methoxy psoralen	C₁₂H₈O₄	[10]
	4	8-methoxy psoralen	C₁₂H₈O₄	[10]
	5	4,5ʹ,8-trioxsalen	C₁₄H₁₂O₃	[11]
	6	imperatorin	C₁₆H₁₄O₄	[11]
	7	bakuchicin	C₁₁H₆O₃	[12]
	8	psoralidin	C₂₀H₁₆O₅	[13]
	9	isopsoralidin	C₂₀H₁₆O₅	[13]
	10	corylidin	C₂₀H₁₆O₇	[14]
	11	psoralidin-2ʹ,3ʹ-oxide	C₂₄H₂₀O₈	[15]
	12	4ʺ, 5ʺ-dehydroisopsoralidin	C₂₀H₁₄O₅	[16]
	13	neopsoralen	C₁₇H₈O₅	[17]
	14	bvacoumestan A	C₂₀H₁₆O₆	[18]
	15	sophoracoumestan A	C₂₀H₁₄O₅	[18]
	16	bvacoumestan B	C₂₀H₁₆O₆	[18]
	17	bavacoumestan C	C₂₀H₁₆O₇	[19]
	18	bavacoumestan D	C₂₀H₁₆O₅	[19]
	19	3ʺ-methoxy-bavacoumestan C	C₂₁H₁₈O₇	[20]
	20	pyranocoumarin	C₂₇H₂₈O₄	[21]
	21	7,2ʹ,4ʹ-trihydroxy-3-aryl-coumarin	C₁₅H₁₀O₅	[22]
	22	psoracoumestan	C₂₀H₁₄O₅	[22]
	23	seputhecarpan A	C₂₀H₁₈O₄	[23]
	24	psoralidinl	C₂₀H₁₆O₅	[24]
Flavonoids	25	corylifol D	C₂₀H₁₆O₅	[25]
	26	corylifol C	C₂₀H₁₈O₅	[26]
	27	4ʹ-methoxyflavone	C₁₆H₁₂O₃	[27]
	28	astragalin	C₂₁H₂₀O₁₁	[10]
	29	3,5,3ʹ,4ʹ-tetrahydroxy-7-methoxyflavone-3ʹ-o-α-l-xylopyranosyl (1 → 3)-o-α-l-arabinopyranosyl (1 → 4)-o-β-d-galactopyranoside	C₃₂H₃₈O₂₀	[28]
	30	bavachin	C₂₀H₂₀O₄	[29]
	31	isobavachin	C₂₀H₂₀O₄	[29]
	32	bavachinin A	C₂₁H₂₂O₄	[29]
	33	6,7-furanbavachinone B	C₂₀H₁₈O₅	[20]
	34	bavachinone B	C₂₀H₁₈O₅	[30]
	35	bavachinone A	C₂₀H₂₀O₅	[30]
	36	brosimacutin D	C₂₀H₂₀O₅	[24]
	37	brosimacutin E	C₂₀H₂₀O₅	[24]
	38	6-prenylnaringenin	C₂₀H₂₀O₅	[31]
	39	bakuisoflavone	C₂₀H₁₈O₅	[32]
	40	7, 8-Dihydro-8- (4-hydroxyphenyl) -2, 2-dimethyl-2H, 6H-[1, 2-b:5, 4-b]dipyran-6’-one)	C₂₀H₁₈O₄	[33]
	41	furano (2ʺ,3ʺ,7,6)-4ʹ-hydroxyflavanone	C₁₇H₁₂O₄	[34]
	42	2(S)-6- methoxy-7-hydroxymethylene-4ʹ-hydroxyl-flavanone	C₁₇H₁₆O₅	[20]
	43	corylifol F	C₁₇H₁₄O₅	[35]
	44	corylifol G	C₂₅H₂₆O₅	[35]
	45	bakuflavanone	C₂₀H₂₀O₅	[32]
	46	isoneobavaisoflavone	C₂₀H₁₈O₄	[26]
	47	corylifol A	C₂₅H₂₆O₄	[26]
	48	erythrinin A	C₂₀H₁₆O₄	[26]
	49	5,7,4ʹ-trihydroxyisoflavone	C₁₅H₁₀O₅	[34]
	50	7-O-methylluteone	C₂₁H₂₀O₆	[24]
	51	corylin	C₂₀H₁₆O₄	[24]
	52	neobavaisoflavone	C₂₀H₁₈O₄	[24]
	53	corylifols D	C₂₀H₁₈O₅	[36]
	54	corylifols E	C₂₀H₁₈O₆	[36]
	55	daidzin	C₂₁H₂₀O₉	[37]
	56	daidzein	C₁₅H₁₀O₄	[38]
	57	biochanin A	C₁₆H₁₁O₅	[38]
	58	7-O-methylcorylifol A	C₂₆H₂₈O₄	[39]
	59	7-O-Isoprenylneobavaisoflavone	C₂₅H₂₆O₄	[39]
	60	7-O-Isoprenylcorylifol A	C₃₀H₃₄O₄	[39]
	61	corylinin	C₂₅H₂₆O₄	[40]
	62	neocorylin	C₂₅H₂₄O₄	[41]
	63	8-prenyldaidzein	C₂₀H₁₈O₄	[42]
	64	bavadin	C₂₇H₃₀O₁₃	[43]
	65	bavarigenin	C₂₂H₂₂O₇	[43]
	66	corylinal	C₁₆H₁₀O₅	[44]
	67	corylinal methyl ether	C₁₇H₁₂O₅	[45]
	68	psoralenol	C₂₀H₁₈O₅	[46]
	69	7-Methoxybakuchiol	C₂₁H₂₀O₅	[46]
	70	3″-acetoxy-7-methoxybakuchiol	C₂₃H₂₂O₆	[46]
	71	3″,7-acetoxybakuchiol	C₂₄H₂₂O₇	[46]
	72	wighteone	C₂₀H₁₈O₅	[22]
	73	isowighteone	C₂₀H₁₈O₅	[22]
	74	neo-bavaisoflavone	C₂₀H₁₈O₄	[30]
	75	4ʹ,7-dihydroxy-3ʹ-(6″ β-hydroxy-3ʺ,7ʺ-dimethyl-,2ʺ,7ʺ-dibutenyl)-geranylisoflavone	C₂₅H₂₆O₅	[20]
	76	4ʹ,7-dihydroxy-3ʹ-(7ʺ-hydroxy-7ʺ-methyl-2ʺ,5ʺ-dibutenyl)-geranylisoflavone	C₂₅H₂₆O₅	[20]
	77	corylisoflavone A	C₁₈H₁₈O₆	[47]
	78	bavachalcone	C₂₀H₂₀O₄	[29]
	79	Isobavachalcone	C₂₀H₂₀O₄	[29]
	80	Isoneobavachalcone	C₁₅H₁₂O₅	[29]
	81	isobavachromene	C₂₀H₁₈O₄	[48]
	82	Bavachromene	C₂₀H₁₈O₄	[49]
	84	4,2ʹ-Dihydroxy-4ʹ-methoxy-5ʹ-(3″,3″-dimethylallyl)-chalcone	C₂₁H₂₂O₅	[23]
	84	Bakuchalcone	C₂₀H₂₀O₅	[50]
	85	brosimacutin G	C₂₀H₂₀O₆	[26]
	86	corylifol B	C₂₀H₂₀O₅	[26]
	87	Psorachalcone A	C₂₀H₂₀O₅	[51]
	88	Psorachalcone B	C₂₀H₂₀O₅	[51]
89	bavachromanol	C₂₀H₂₀O₅	[52]
90	neobavachalcone	C₁₇H₁₄O₆	[53]
91	3,4- furanbavachalcone A	C₂₁H₂₂O₆	[20]
92	4,5- furanbavachalcone A	C₂₀H₂₀O₆	[20]
93	4,2ʹ-dihydroxy-2″ -(1‴-methylethyl)-2″-3″-dihydro-(4″,5″,3ʹ,4ʹ) furano chalkone	C₂₀H₂₀O₄	[54]
94	4ʹ-O-methylbavachalcone	C₂₁H₂₂O₄	[54]
95	xanthoangelol	C₂₅H₂₈O₄	[22]
96	Artonin ZA	C₂₀H₁₈O₄	[35]
Monoterpene phenols	97	bakuchiol	C₁₈H₂₄O	[55]
	98	bisbakuchiols A	C₃₆H₄₆O₄	[56]
	99	bisbakuchiols B	C₃₆H₄₆O₄	[56]
	100	corylifolin	C₁₃H₁₆O	[57]
	101	bisbakuchiols C	C₃₆H₄₈O₃	[58]
	102	cyclobakuchiol A	C₁₈H₂₄O	[59]
	103	cyclobakuchiol B	C₁₈H₂₄O	[59]
	104	2,3-epoxybakuchiol	C₁₈H₂₄O₂	[59]
	105	Δ¹,3-hydroxybakuchiol	C₁₈H₂₄O₂	[59]
	106	Δ³,2-hydroxybakuchiol	C₁₈H₂₄O₂	[59]
	107	cyclobakuchiol C	C₁₈H₂₆O₂	[60]
	108	13-methoxyisobakuchiol	C₁₉H₂₆O₂	[61]
	109	13-ethoxyisobakuchiol	C₂₀H₂₈O₂	[61]
	110	12,13- dihydro-13-hydroxybakuchiol	C₁₈H₂₆O₂	[61]
	111	Δ¹⁰-12,13-dihydro-12-(R)-methoxyisobakuchiol	C₁₉H₂₆O₂	[61]
	112	Δ¹⁰-12,13-dihydro-12-(S)-methoxyisobakuchiol	C₁₉H₂₆O₂	[61]
	113	15-demetyl-12,13-dihydro-13-ketobakuchiol	C₁₇H₂₂O₂	[61]
	114	Δ^1,3-bakuchiol	C₁₈H₂₂O	[61]
	115	12R,13-diolbakuchiol	C₁₈H₂₆O₃	[24]
	116	12S,13-diolbakuchioll	C₁₈H₂₆O₃	[24]
	117	psoracorylifol A	C₁₈H₂₄O₃	[62]
	118	psoracorylifol B	C₁₈H₂₄O₃	[62]
	119	psoracorylifol C	C₁₈H₂₄O₃	[62]
	120	psoracorylifol D	C₁₈H₂₄O₂	[62]
	121	psoracorylifol E	C₁₈H₂₄O₂	[62]
	122	psoracorylifol F	C₁₈H₂₄O₂	[63]
	123	psoralen ether	C₂₃H₃₀O	[64]
	124	psoracorylifol G	C₁₉H₂₆O	[64]
	125	psoracorylifol H	C₁₈H₂₄O₃	[64]
	126	bisbakuchiol V	C₃₆H₄₈O₄	[64]
	127	bisbakuchiol M	C₃₆H₄₀O₄	[65]
	128	bisbakuchiol N	C₃₆H₄₆O₂	[65]
	129	bisbakuchiol O	C₃₆H₄₆O₂	[65]
	130	bisbakuchiol P	C₃₆H₄₆O₂	[65]
	131	bisbakuchiol Q	C₃₆H₄₆O₃	[65]
	132	bisbakuchiol R	C₃₇H₅₀O₄	[65]
	133	bisbakuchiol S	C₃₇H₅₀O₄	[65]
	134	bisbakuchiol T	C₃₆H₄₆O₃	[65]
	135	bisbakuchiol U	C₃₆H₄₆O₃	[65]
	136	bakuchiol ether A	C₂₉H₄₂O₂	[65]
	137	bakuchiol ether B	C₃₃H₅₀O₂	[65]
	138	bakuchiol ether C	C₃₂H₄₆O₂	[65]
	139	Δ¹¹-12-hydroxy-12-dimethyl bakuchiol	C₁₈H₂₄O₂	[20]
Benzofurans	140	corylifonol	C₁₃H₁₄O₄	[66]
	141	isocorylifonol	C₁₃H₁₄O₄	[66]
	142	butylcnideoside A	C₂₁H₂₆O₉	[67]
	143	dihydrobutylcnideoside A	C₂₁H₂₈O₉	[67]
	144	isopsoralenoside butyl ester	C₂₁H₂₆O₉	[67]
	145	dihydroisopsoralenoside butyl ester	C₂₁H₂₈O₉	[67]
	146	isopsoralenoside methyl ester	C₁₈H₂₀O₉	[67]
	147	dihydroisopsoralenoside methyl ester	C₁₈H₂₂O₉	[67]
	148	psoralenoside	C₁₇H₁₈O₉	[68]
	149	isopsoralenoside	C₁₇H₁₈O₉	[68]
Other compounds	150	glycerol monoesters	C₂₁H₄₄O₃	[69]
	151	glycerol diesters	C₂₇H₅₂O₅	[69]
	152	triacylglycerols	C₃₉H₇₄O₆	[69]
	153	raffinose	C₁₁H₂₀O₁₀	[69]
	154	daucosterol	C₃₅H₆₀O₆	[69]
	155	palmitic acid	C₁₆H₃₂O₂	[70]
	156	stearic acid	C₁₈H₃₆O₂	[70]
	157	linoleic acid	C₁₈H₃₂O₂	[70]
	158	β-stigmasterol	C₂₉H₄₈O	[70]
	159	pinitol	C₇H₁₄O₆	[71]
	160	uracil	C₄H₄N₂O₂	[37]
	161	p-hydroxybenzaldehyde	C₇H₆O₂	[72]
	162	methyl p-hydroxybenzoate	C₈H₈O₃	[16]
	163	psoralester	C₂₂H₃₈O₄	[49]

Back to article page

ISSN: 1749-8546

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com

Chinese Medicine

Contact us