Skip to main content

Table 5 Summary of CoMSIA models for different combinations of three fields

From: Isolation, bioassay and 3D-QSAR analysis of 8-isopentenyl flavonoids from Epimedium sagittatum maxim. as PDE5A inhibitors

Models

Fieldsa

q2

r2

SEE

F value

Components

1

SHA

0.505

0.999

0.042

1663.955

7

2

HAD

0.477

0.970

0.252

107.115

3

3

EHA

0.439

0.968

0.258

101.590

3

4

SAD

0.413

0.974

0.245

84.985

4

5

ESA

0.388

0.979

0.222

104.013

4

6

ESD

0.377

0.669

0.761

24.212

1

7

SHD

0.375

0.967

0.264

97.025

3

8

EAD

0.375

0.629

0.805

20.366

1

9

EHD

0.362

0.961

0.286

82.351

3

10

ESH

0.342

0.972

0.242

116.168

3

  1. aA hydrogenbond acceptor, D hydrogenbond donor, E electrostatic, S steric, H hydrophobic
Back to article page

Chinese Medicine

ISSN: 1749-8546

Contact us