Fig. 5

KXS decreases the expression of mitochondrial fission and fusion-related proteins and increases the expression of neurotrophic factors and synaptic proteins in the hippocampus of APP/PS1 mice. A Expression of Mfn1, Mfn2, p-Drp1 and Drp1; B Expression of BDNF, NGF, SYN and PSD95; C–E Histogram of relative expression of Mfn1, Mfn2, p-Drp1 and Drp1; F–I Histogram of relative expression of BDNF, NGF, SYN and PSD95. KXS-H: 10 g/kg/day. The experiment data are expressed as means ± SEM. n = 3 in each group. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. Ctrl group; *P < 0.05, **P < 0.01, ***P < 0.001 vs. APP/PS1 group