Fig. 2

Effect of BSTL on biochemical indicators and renal histological changes in db/db mice. A Quantitative assessment of body weight, random blood glucose, UACR, Scr, BUN, ALT and AST of mice. B Representative micrographs of HE-stained kidney sections (× 200), PAS-stained kidney sections (× 400), and Masson’s trichrome-stained kidney sections (× 400) from different groups. Scale bar, 30 µm. The arrows indicate representative pathological changes. C Quantitative assessment of mesangial matrix by PAS staining and collagen deposition in glomeruli. ^*P < 0.05 vs. con; ^**P < 0.01 vs. con; ^#P < 0.05 vs. db/db; ^##P < 0.01 vs. db/db. con, control mice; db/db, db/db mice; db/db + B, db/db mice treated with BSTL