Fig. 3

Effect of BSTL on podocyte injury in vivo. A Representative TEM micrographs of the kidneys of mice from different groups (× 15 000, × 50 000). Scale bar, 1 µm. B Representative western blots and quantitative assessment of nephrin, podocin, and cleaved caspase-3 in the kidneys of mice. C IHC staining of renal sections and quantitative assessment for nephrin, podocin, and cleaved caspase-3 (× 400). Scale bar, 30 µm. D TUNEL staining and quantitative assessment in renal sections from different groups (× 400). Scale bar, 30 µm. ^*P < 0.05 vs. con; ^**P < 0.01 vs. con; ^#P < 0.05 vs. db/db; ^##P < 0.01 vs. db/db. con, control mice; db/db, db/db mice; db/db + B, db/db mice treated with BSTL