Fig. 7
From: Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect. In the continuous inflammatory phase, SJS could inhibit the NF-kB/NLRP3 axis and suppress the pyroptosis, thus alleviating inflammatory response. As the disease progresses, immunosuppression was seen and SJS could enhance the NF-kB/NLRP3 axis and promote the pyroptosis, thus boosting immune response