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Fig. 10 | Chinese Medicine

Fig. 10

From: A novel microbial and hepatic biotransformation-integrated network pharmacology strategy explores the therapeutic mechanisms of bioactive herbal products in neurological diseases: the effects of Astragaloside IV on intracerebral hemorrhage as an example

Fig. 10

CA suppresses BV2 proliferation and migration, but ASIV does not. A CCK-8 shows that CA inhibits BV2 proliferation. B CCK-8 shows that ASIV doesn’t affect BV2 proliferation. C Scratch assay suggests that CA inhibits BV2 migration. D Scratch assay suggests that CA doesn’t inhibit BV2 migration. E Representative image of the scratch assay for CA. F Representative image of the scratch assay for ASIV. G Representative images of WB show that CA decreases FAK and CDC42 expressions. H The statistical graph shows that ASIV doesn’t affect the FAK level. I The statistical graph shows that CA decreases FAK expression. J The statistical graph shows that ASIV doesn’t affect CDC42 expression. K The statistical graph shows that CA suppresses the CDC42 level. Data are expressed as mean ± SD, n = 3. *P < 0.05, **P < 0.01, ***P < 0.001. Scale bar = 100 μm (E–F)

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Chinese Medicine

ISSN: 1749-8546

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