Skip to main content
Fig. 9 | Chinese Medicine

Fig. 9

From: A novel microbial and hepatic biotransformation-integrated network pharmacology strategy explores the therapeutic mechanisms of bioactive herbal products in neurological diseases: the effects of Astragaloside IV on intracerebral hemorrhage as an example

Fig. 9

The effects of orally administrated ASIV on CDC42 and CSF1R after ICH. A The representative double-staining images of Iba1 (green) and CSF1R (red) show that ASIV decreases CSF1R expression. B The enlarged images show that CSF1R is mainly expressed in microglia/macrophage. C The statistical graph indicates that ASIV suppresses the expression of CSF1R. D The statistical graph indicates that ASIV suppresses the expression of CDC42. E The enlarged images show that CDC42 (red) is highly expressed on Iba1-positive microglia/macrophage (green). F The representative double-staining images of Iba1 and CDC42 show ASIV decreases CDC42 expression. Data are expressed as mean ± SD, n = 5. *P < 0.05, ***P < 0.001, ****P < 0.0001. Scale bar = 50 μm

Back to article page

Chinese Medicine

ISSN: 1749-8546

Contact us