Fig. 1

MON enhanced the survival of IL-1β-treated chondrocytes. A The molecular structure of MON. B The cell counting kit-8 assay showing the cell viability in different concentration of MON (0–1000 μM) for 24 h. C, D The cell counting kit-8 assay showing the cell viability of chondrocytes pretreatment with or without 10 ng/ml IL-1β for 24 h, followed by treatment with different concentration of MON (0, 25, 50 and 100 μM) for 24 h or 48 h. E Edu staining showing the proliferation of chondrocytes pretreated with or without 10 ng/ml IL-1β for 24 h, followed by treatment with different concentration of MON (0, 25, 50 and 100 μM) for another 24 h. F Quantification of Edu positive cells. All experiments were performed in triplicated and data were presented as the mean ± SD, n = 3 per group. *P < 0. 05, **P < 0. 01