Fig. 6

MON alleviated OA progression and promoted cartilage repair in DMM mice. A–D The pre-experimental results suggested that the concentration of 100 μM MON showed significant statistical difference. E DMM mice model and MON treatment protocol. F Safranin O-Fast Green and HE staining of mice knee joints were performed to assess the histological morphology of the different groups at 56 days after MON treatment. G The OARSI scores of the different groups were calculated respectively at 56 days after MON treatment. All experiments were performed in triplicated and data were presented as the mean ± SD, n = 3 per group. *P < 0. 05, **P < 0. 01