Table 1 Molecular docking results
NO | Proteins | PDB ID | Test compounds | Affinity (kcal/mol) |
|---|---|---|---|---|
1 | SRC | 2H8H | Genkwanin | −9.0 |
2 | SRC | 2H8H | Norwogonin | −8.9 |
3 | SRC | 2H8H | Moslosooflavone | −8.6 |
4 | SRC | 2H8H | 5,7,4'-Trihydroxy-8-methoxyflavone | −8.6 |
5 | SRC | 2H8H | 3-Methylkempferol | −8.6 |
6 | SRC | 2H8H | 5,2'-Dihydroxy-6,7,8-trimethoxyflavone | −8.4 |
7 | EGFR | 5WB7 | 5,7,4'-Trihydroxy-8-methoxyflavone | −8.3 |
8 | EGFR | 5WB7 | Genkwanin | −8.2 |
9 | EGFR | 5WB7 | Norwogonin | −8.0 |
10 | SRC | 2H8H | 5,7,2,5-Tetrahydroxy-8,6-dimethoxyflavone | −7.8 |
11 | EGFR | 5WB7 | Moslosooflavone | −7.8 |
12 | EGFR | 5WB7 | 4'-Methylcapillarisin | −7.8 |
13 | EGFR | 5WB7 | 5,7,2,5-Tetrahydroxy-8,6-dimethoxyflavone | −7.5 |
14 | EGFR | 5WB7 | 3-Methylkempferol | −7.5 |
15 | EGFR | 5WB7 | 5,2'-Dihydroxy-6,7,8-trimethoxyflavone | −7.1 |
16 | AKT1 | 1UNQ | 4'-Methylcapillarisin | −6.2 |
17 | AKT1 | 1UNQ | 5,7,2,5-Tetrahydroxy-8,6-dimethoxyflavone | −6.2 |
18 | AKT1 | 1UNQ | 3-Methylkempferol | −5.8 |