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Table 1 Common self-assembly forces in CSAN

From: Formation of a traditional Chinese medicine self-assembly nanostrategy and its application in cancer: a promising treatment

Self-assembly force

Self-assembly mechanism

Active ingredient

Primary source

Structure

Refs.

Hydrogen bond

Hydrogen bond

OA

Glossy privet fruit

[19]

PTX

Taxus chinensis

Hydrogen bond and Hydrophobic interaction

OA

Glossy privet fruit

[29]

GA

Licorice

Hydrogen bond and π-π stacking

BBR

Coptis chinensis

[17]

CA

Cinnamon

bark

Hydrogen bond and van der Waals forces

Sito

Arisaema heterophyllum Blume

[28]

Hydrophobic interaction

Hydrophobic interaction

GW

Daphne genkwa

[38]

GA

Licorice

Hydrophobic interaction and hydrogen bond

UA

Loquat leaf

[12]

Hydrophobic interaction and π-π stacking

Cela

Tripterygium wilfordii

[41]

Hydrophobic interaction and electrostatic interaction

WOG

Baikal skullcap

[20]

BBR

Coptis chinensis

Electrostatic interaction

Electrostatic interaction and hydrophobic interaction

BA

Baikal skullcap

[20]

BBR

Coptis chinensis

Ï€-Ï€ stacking

Ï€-Ï€ stacking and hydrogen bond

Rhe

Rheum officinale

[18]

Ï€-Ï€ stacking, van der Waals forces, and hydrogen bond

LDA

Liquidambar formosana

[14]

Coordination interaction

Coordination interaction

Lut

Lonicera japonica Thunb

[15]