Fig. 2

In LPS-induced pulmonary fibrosis, CAE blocked α-SMA and COL1A1 expression and amount of HYP in tissue and serum. A, B Representative immunohistochemical staining of COL1A1 and α-SMA. The scale bar is 100 μm. C, D Quantification of histological changes in different treatment groups with positive area using Image J analysis software (n = 8). E Quantitative analysis of COL1A1 expression (n = 8). F, G Quantitative analysis of HYP expression in serum and lung tissues (n = 8). All data were presented as means ± SEM. * P< 0.05, ** P  <0.01, ***P < 0.001 vs. the LPS group,^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. Alone group