Fig. 4From: Altered gut microbiota–host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency patternBA-transforming metagenomic signature of IBS-D patients with LDSD or non-LDSD pattern. A Relative abundances of 9 BA-transforming genes; B, C Functional estimation of bacterial bile salt hydrolase and 7-de hydroxylase activities based on the ratios of products to substrates of the two BA-transforming reactions; D Relative abundances of bsh-expressing genera; E–H Relative abundances of bai-expressing species. Statistical results were obtained from one-way ANOVA with the three-group comparison and Mann–Whitney test with the two-group comparison (*p < 0.05 vs. controls; #p < 0.05; ##p < 0.01 vs. the non-LDSD pattern)Back to article page