Fig. 6

Effects of Z-LIG and NUR77/NOR1 on mitochondrial transcription and translation in HL-60 cells. A–C The mRNA levels were measured using qPCR after treatment with Z-LIG (24 h) or transfection with the plasmid in HL-60 cells. D–G HL-60 cells were transfected with the plasmid or treated with Z-LIG as indicated for 48 h. Total protein samples were analyzed using western blotting for MYC, COX II, and COX IV. E was densitometric analyses of the western blots shown in D, and G was densitometric analyses of the western blots shown in F. Values are presented as the means ± SD (n = 3 per group). *P < 0.05, ** P < 0.01, and *** P < 0.001 vs. CTRL. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. Vector