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Table 1 The anti-cancer properties of some typical GLT compounds

From: A review of anti-tumour effects of Ganoderma lucidum in gastrointestinal cancer

GLT

Cancer

Anti-cancer mechanisms

Refs.

Inhibiting proliferation

Inducing apoptosis

Inhibiting metastasis

Regulating autophagy

GA

Hepatoma

 + 

−

−

−

[27]

GA-A

HCC

 + 

 + 

 + 

−

[28, 29]

GA-A

Neuroblastoma

 + 

−

−

−

[30]

GA-A

Glioblastoma

 + 

 + 

−

 + 

[31]

GA-A

Lung cancer

 + 

−

 + 

−

[32]

GA-A

Pancreatic cancer

 + 

−

−

−

[33]

GA-A

Cancer

 + 

 + 

−

−

[34]

GA-A

Brain glioma

 + 

−

−

−

[35]

GA-A

Prostate cancer

 + 

 + 

−

−

[36, 37]

GA-D

ESCC

 + 

 + 

−

 + 

[38]

GA-D

CRC

−

 + 

−

−

[39]

GA-DM

Breast cancer

 + 

 + 

−

−

[40]

GA-Me

CRC

 + 

 + 

−

−

[41]

GA-Me

Lung cancer

−

 + 

 + 

−

[42,43,44]

GA-T

Lung cancer

 + 

 + 

−

−

[45, 46]

GA-T

Colon cancer

 + 

−

 + 

−

[47, 48]

GA-T

Cervical cancer

 + 

 + 

−

−

[49]

GA-A/DM

Meningioma

 + 

 + 

−

−

[50]

GA-A/H

Breast cancer

 + 

-

 + 

−

[51]

GA-T/Mk

Cervical cancer

−

 + 

−

−

[52]

GA-Mf/S

Cervical carcinoma

−

 + 

−

−

[53]

LA-B

Hepatoma

−

−

 + 

−

[54]

Lucidumol D

Cancer

 + 

−

−

−

[55]

GAEE

Breast cancer

−

−

 + 

−

[56]

  1. ESCC Esophageal squamous cell carcinoma; GAEE G. lucidum extract mainly contains GA dihydrogenated GA and GA isomer
  2.  + : have the properties; -: lack of this properties